Exploring new zolpidem binding site on ε-containing Gaba (A) receptor via computational methods

The ε-containing GABA (A) receptors (GABAARs), a lesser-studied subtype within the GABAAR family, have gained attention due to their distinct pharmacological properties and potential involvement in brain injury. Zolpidem (ZPM), a widely used Z-drug, has been reported to induce paradoxical effects in...

Full description

Bibliographic Details
Main Author:	Tze, Sherilyn Choo Ming
Format:	Thesis
Language:	English
Published:	2025
Subjects:	R Medicine RA Public aspects of medicine
Online Access:	http://eprints.usm.my/63471/
Abstract	Abstract here

Similar Items

Novel binding sites on GABA (A) receptors for the alternative effects of zolpidem: in vivo and in silico studies
by: Mohamad, Fatin Hilyani
Published: (2023)

The anxiety effect of a generalized epilepsy rat model treated with zolpidem
by: Murugan, Sutharshinnii A/P
Published: (2025)

Exploring the effects of zolpidem on cognitive impairment and cellular changes using a lithium-pilocarpine rat model
by: Ahmed, Iman Imtiyaz
Published: (2021)

Voltage Clamp Electrophysiology Screening Of Selected Compounds From Zizyphus Mauritiana And Myristica Fragrans On Specific GABA Receptors
by: Che Has, Ahmad Tarmizi
Published: (2012)

Changes of GABA receptor and immunoreactivity modification of IP3 & BDNF-TrkB in KA-induced rat epileptogenic hippocampal neuronal culture
by: Nei, Chong Pei
Published: (2018)

In Silico Selection And Validation Of Dna Aptamer Against Progesterone Receptor Dna Binding Domain
by: Tholasi Nadhan, Navien
Published: (2022)

Evaluation of the dopamine and serotonin receptor binding activity of selected aporphines / Vani A/P Munusamy
by: Vani, Munusamy
Published: (2012)

The effects of zolpidem on spatial memory, cellular and ionic co-transporters (KCC2/NKCC1) in the hippocampus of lithium-pilocarpine rat model
by: Othman, Muhammad Zulfadhli
Published: (2022)

Relationship between site of facial nerve injury and electroneuronography : a retrospective study
by: Rajoo, Tamil Selvi
Published: (2023)

A poly (octanediol citrate)/gallium-containing bioglass composite for bone tissue regeneration / Ehsan Zeimaran
by: Ehsan , Zeimaran
Published: (2016)

Identification Of A Cd36 Scavenger Receptor Binding Peptide Using A 12-Mer Peptide M13 Phage Display Library
by: Ayob, Muhammad Salahuddin
Published: (2018)

Antimicrobial effects on streptococcus mutans and candida albicans and cytotoxicity study on human periodontal ligament fibroblast cell line of oxy-ionic solution at various ph levels - an in vitro study
by: Ming, Xu
Published: (2025)

Exploration of handwritten allographic features attributed to the primary educational backgrounds of Malaysian writers for forensic comparison
by: Gannetion, Linthini A/P
Published: (2023)

Binding activity of duffy binding protein (PkDBPaII) of Plasmodium Knowlesi clinical isolates from Peninsular Malaysia and Malaysian Borneo / Lim Khai Lone
by: Lim, Khai Lone
Published: (2018)

Alternative method to develop new strategy in ordinal regression: a case study in dental
by: Lazin, Muhamamd Amirul Mat
Published: (2025)

Kajian Reseptor Gaba Periferal Secara In - Vitro
by: Mohd, Nik Samsabaharani
Published: (1983)

Elucidation of serum interleukin-35 levels and interleukin-35 receptors in systemic lupus erythematosus patients: association with serological parameters and disease activity
by: Shukri, Nur Diyana Mohd
Published: (2021)

The effects of sirna-targeting IL-17a receptor in regulating the osteogenic differentiation in stem cells from human exfoliated deciduous teeth
by: Aduni, Wan Khairunnisaa Wan Nor
Published: (2024)

Combination of gravid ovipositing sticky trap and NS1 antigen test: New paradigm for dengue vector surveillance in Selangor Malaysia / Lau Sai Ming
by: Lau, Sai Ming
Published: (2018)

The evaluation of high-and moderate-intensity interval exercise on perceptual responses, physical health, quality of life, mental well-being and exercise motivation among college students in China
by: Ming, Chang
Published: (2025)

In vitro inhibitory effects of compounds from several medicinal plants on prostaglandin E2 (PGE2) production in human plasma and Platelet-Activating Factor (PAF) receptor binding
by: Siti Norafiqah Mohd Sazali (P78683)
Published: (2023)

Comparison of immediate release oral oxycodone hydrochloride(kappa 2 receptor agonist) with oral pantoprazole in the treatment of functional dyspepsia
by: Omar, Azaharim
Published: (2012)

In vitro inhibitory effects of compounds from several medicinal plants on prostaglandin E2 (PGE2) production in human plasma and Platelet-Activating Factor (PAF) receptor binding
by: Siti Norafiqah Mohd Sazali (P78683)
Published: (2023)

Exploring the awareness and acceptance of UiTM Selangor students towards genetically modified (GM) rice / Noraini Saripudin
by: Saripudin, Noraini
Published: (2019)

Characterization of candidate receptor proteins that bind dengue viruses using proteomics
by: Jong, Wan Wui.
Published: (2006)

The associated factors of depression and quality of life in patients with diabetic foot ulcer in Hospital Tengku Ampuan Afzan / Chan Tze Lin
by: Chan, Tze Lin
Published: (2016)

Measles vaccination programme in Sarawak - an evaluation of service provision and uptake / Chai Phing Tze
by: Chai, Phing Tze
Published: (2016)

Evaluation of lignosus rhinocerus aqueous extract on muscarinic receptor in isolated trachea of sprangue-dawley rats
by: Taha, Syed Muhamad Asyraf Syed
Published: (2019)

The unmet needs among working mothers of children with epilepsy attending specialist hospitals in Kelantan: a mixed methods study
by: Abdullah, Noor Aida
Published: (2024)

Knowledge, attitude, and practice (KAP) questionnaire on melioidosis: development and validation and associated factors among field agricultural farmers in Kelantan, Malaysia
by: Abdullah, Nor Azlina
Published: (2024)

Bioassay-guided profiling of quercus infectoria gall extracts using hplc and their antimalarial activity
by: Hamidon, Nurul Hammizah
Published: (2025)

Translation and validation of NIOSH worker’s well-being questionnaire among healthcare workers (Wellbq)
by: Sampil, Nionella Stephen
Published: (2023)

Risk perception on needlestick injury and effectiveness of the needlestick prevention module among house officers in Kelantan
by: Kutubudin, Ahmed Farrasyah Mohd
Published: (2024)

Proportion of the processed food and ultra-processed food (UPF) consumption and its associated factors among adults attending general clinics in Hospital Universiti Sains Malaysia
by: Husain, Mohd Hilmi Mat
Published: (2024)

Prevalence and factors associated with serologically confirmed yaws infection among orang asli population in Hulu Terengganu, Malaysia
by: Hashim, Muhammad Aminuddin Che
Published: (2024)

Men’s health behaviors among public safety personnel in Kelantan: a prediction and mediation analysis
by: Mukhti, Muhammad Iqbal
Published: (2024)

Commuting injury among ministry of health staff in Kelantan, Malaysia from 2016 to 2022 and its associated factors
by: Sabri, Muhammad Ruhaifi Muhammad
Published: (2024)

Validity and reliability of the Malay translated version of the diabetes health literacy scale among Malaysian adults with type 2 diabetes mellitus
by: Ling, Ng Pei
Published: (2024)

Poor sleep quality and its associated factors among nurses in tertiary hospitals, Kelantan
by: Supian, Nur Shuhaiza
Published: (2024)

Time to non-persistence of sodium-glucose co-transporter 2 inhibitors and its prognostic factors among patients with type 2 diabetes in Universiti Malaya Medical Centre
by: Sofian, Nurul Farhana Mohd
Published: (2024)