| 要約: | Background: There are multiple methods available for diagnosing coronary artery
disease (CAD), including myocardial perfusion imaging (MPI). One of the challenges to
interpret MPI findings is the interfering sub-diaphragmatic activity with appropriate
cardiac visualisation. Various methodologies were assessed in order to overcome this
issue. A relatively common method is the consumption of fatty meals before proceeding
with the scan. Nevertheless, consumption of high-fat meals may result in adverse effects
for certain patients, in addition to incurring additional expenses. The aim of this study is
to investigate the impact of consuming a high-fat meal, milk, or water before
undergoing MPI and to aid in the interpretation of the results.
Methods: A total of 150 patients (age 58.86 ± 12.05 years) were enrolled in this study.
The patients were randomly divided into three groups. These patients underwent a
two-day protocol of MPI. During the day of the pharmacological stress study, they were
given a fatty meal. During the rest study, fifty the patients in Group 1 were given a fatty
meal, fifty in Group 2 were given 350 ml of milk and fifty patients in Group 3 were
given 350 ml of water. The study was double blinded for both patients and interpreters.
Stress and rest MPI studies were performed for all patients and the sub-diaphragmatic
activity was determined visually, and semi-quantitatively on the reconstructed images.
Results: The difference between all groups, as determined by semi-quantitative and
visual evaluations, is not statistically significant.
Conclusion: The findings of this comparative study indicated that scans conducted after
preparing fatty meal, milk, and water prior to MPI yielded similar interpretations and
image quality.
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