| Summary: | Introduction: Massive transfusion protocol (MTP) was designed to improve the outcome
of patients at risk of mass ive haemorrhage. This study focused on the prevalence,
indications, associated factors toward the indication of MTP cases and 24-hour mortality
among who received MTP in Hospital USM.
Methods: A retrospective cross-sectional study was performed on 110 patients for whom
MTP was activated in Hospital USM. Data were extracted from the medical records and
blood bank system (MyTransfus i). Simple and multiple logistic analysis was used for
stati stical analysis, and a p-value of< 0.05 was considered significant.
Results: A total of 273,087 patients were admitted to Hospital USM and 193 patients
required MTP activation during the study period. The prevalence of MTP activation was
only 0.07%. This study included 110 MTP cases which consisted of 62 (56.3%) trauma
and 48 (43 .7%) non-trauma patients. The mean age of total patients were 40.0 years old,
and maj ority were male (66.4%). The two most common MTP indications were motor
vehicle accidents (n = 58) and gastrointestinal bleeding (n = 24). Female (adjusted OR=
20.08, 95% CI 5.76- 70.00, p <0.00 I) and presence of comorbidity (adjusted OR= 13.66,
95% CI 4.21 - 44.39, p<0.001) significantly associated with MTP indication. Meanwhile,
no emergency procedure (adjusted OR= 12.77, 95% CI 4.22- 38.61, p <0.001) and noncompliance to MTP (adjusted OR = 4.30, 95% CI l.21 - 15.38, p = 0.024) were
significantly associated with high mortality within 24-hour post MTP activation.
Conclusion: The prevalence of MTP was low. Our result suggested that early emergency
procedures to control the haemorrhage source should be done, and compliance towards
MTP needs to be improved for better patient outcomes.
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