Case-based reasoning retrieval access control model for telecardiology

Also available in printed version : RC78.7.D53 A45 2014 raf

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Ali Saifullah Jasmy
مؤلفون آخرون: Siti Hajar Othman, supervisor
التنسيق: Master's thesis
منشور في: Universiti Teknologi Malaysia 2025
الموضوعات:
الوصول للمادة أونلاين:https://utmik.utm.my/handle/123456789/101682
Abstract Abstract here
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author Ali Saifullah Jasmy
author2 Siti Hajar Othman, supervisor
author_facet Siti Hajar Othman, supervisor
Ali Saifullah Jasmy
author_sort Ali Saifullah Jasmy
description Also available in printed version : RC78.7.D53 A45 2014 raf
format Master's thesis
id utm-123456789-101682
institution Universiti Teknologi Malaysia
publishDate 2025
publisher Universiti Teknologi Malaysia
record_format dspace
record_pdf Abstract
spelling utm-123456789-1016822025-08-21T08:20:49Z Case-based reasoning retrieval access control model for telecardiology Ali Saifullah Jasmy Siti Hajar Othman, supervisor Diagnostic imaging Radiography, Medical -- Digital techniques Also available in printed version : RC78.7.D53 A45 2014 raf This thesis presents the simulation of an integrated dual nanoprobemicrofluidic system for single cell electrical characterizations. Recent cell studies have shown a possible early disease diagnosis at a single cell level by characterizing its electrical properties. One of the studies uses a dual nanoprobe showing its ability in quantitatively detecting single cell viability. However, this method has low throughput rate, high skilled labour requirement and bulky system. We propose an improved system that overcomes these limitations. This study is divided into five stages. The first stage focuses on deciding the system concept and nanoprobe design. The second stage involves nanoprobe characterization which is based on electrical and mechanical properties of five different materials: Silver, Copper, Aluminium, Tungsten and Zinc. The third stage is a single cell modeling of Saccharomyces cerevisiae for mechanical and electrical model. The fourth stage is nanoprobe integration with microfluidic system. The final stage is single cell electrical property characterizations. From the study, several findings were obtained and concluded. First, the most preferred material for nanoprobe is Tungsten which has low electrical resistance of 5.5 O and can withstand an external force up to 35.6 µN before failure. Second, the two layers cell model was validated by displaying a close agreement in terms of penetration force (640 nN) with experimental data. Third, successful cell penetration was achieved at 5.1 pl/min flow rate in 4 µm diameter micro channel. Lastly, insulating the nanoprobe reduces the effect of penetration depth on the current measurement and enables the characterization of single cell cytoplasm electrical conductivity to be realized. Currently the developed system is suitable for cell viability detection application. Furthermore, this system has a potential to be used in single cell thermal measurement, single cell drug delivery and early disease diagnosis atiff UTM 96 p. Thesis (Sarjana Sains Komputer (Keselamatan Maklumat)) - Universiti Teknologi Malaysia, 2014 2025-04-10T04:53:56Z 2025-04-10T04:53:56Z 2014 Master's thesis https://utmik.utm.my/handle/123456789/101682 valet-20160330-145839 vital:85719 Closed Access UTM Complete Unpublished application/pdf Universiti Teknologi Malaysia
spellingShingle Diagnostic imaging
Radiography, Medical -- Digital techniques
Ali Saifullah Jasmy
Case-based reasoning retrieval access control model for telecardiology
thesis_level Master
title Case-based reasoning retrieval access control model for telecardiology
title_full Case-based reasoning retrieval access control model for telecardiology
title_fullStr Case-based reasoning retrieval access control model for telecardiology
title_full_unstemmed Case-based reasoning retrieval access control model for telecardiology
title_short Case-based reasoning retrieval access control model for telecardiology
title_sort case based reasoning retrieval access control model for telecardiology
topic Diagnostic imaging
Radiography, Medical -- Digital techniques
url https://utmik.utm.my/handle/123456789/101682
work_keys_str_mv AT alisaifullahjasmy casebasedreasoningretrievalaccesscontrolmodelfortelecardiology