Fabrication and characterization of electrospunpoly(?-caprolactone) / green tea (camellia sinensis) extract fiber for wound healing
Also available in printed version
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| Autres auteurs: | |
| Format: | Master's thesis |
| Langue: | anglais |
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Universiti Teknologi Malaysia
2025
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| Sujets: | |
| Accès en ligne: | https://utmik.utm.my/handle/123456789/47642 |
| Abstract | Abstract here |
| _version_ | 1854975053780746240 |
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| author | Ainatul Aqilah Mohd. Rashid |
| author2 | Saravana Kumar Jaganathan, supervisor |
| author_facet | Saravana Kumar Jaganathan, supervisor Ainatul Aqilah Mohd. Rashid |
| author_sort | Ainatul Aqilah Mohd. Rashid |
| description | Also available in printed version |
| format | Master's thesis |
| id | utm-123456789-47642 |
| institution | Universiti Teknologi Malaysia |
| language | English |
| publishDate | 2025 |
| publisher | Universiti Teknologi Malaysia |
| record_format | dspace |
| record_pdf | Abstract |
| spelling | utm-123456789-476422025-08-20T20:21:48Z Fabrication and characterization of electrospunpoly(?-caprolactone) / green tea (camellia sinensis) extract fiber for wound healing Ainatul Aqilah Mohd. Rashid Saravana Kumar Jaganathan, supervisor Biomedical engineering Health sciences Also available in printed version The purposes of this study were to fabricate and characterize PCL/green tea extract fibers by electrospinning. The fibers were electrospun at voltage 12 kV, flow rate 0.5 mL/h , 20 cm tip-to-collector distance. The polymeric solutions were prepared in two different solvent-systems and ratio of PCL:green tea extract. In total, 6 fibers were fabricated, namely chloroform:DMF-diluted pure PCL, chloroform:DMF-diluted 11:1 PCL:green tea extract, chloroform:DMF-diluted 10:2 PCL:green tea extract, acetone:DMF-diluted pure PCL, acetone:DMF-diluted 11:1 PCL:green tea extract, and acetone:DMF-diluted 10:2 PCL:green tea extract. Then, the electrospun fibers were characterized in terms of morphological measurement and observation by using SEM, chemical composition analysis by using ATR-FTIR analysis, wettability by water contact angle measurement and lastly, water permeability by water uptake analysis. For both solvent-systems, green tea extract showed to improve the property of pure PCL fiber by decreasing the average and range of fiber diameter produced. Chloroform:DMF-diluted 11:1 PCL/green tea extract fiber produced smaller average (601 � 170 nm) and wider range of fiber diameter (739 nm) compared to chloroform:DMF-diluted 10:2 PCL/green tea extract fiber which produced higher average (663 � 159 nm) and smaller range of fiber diameter (691 nm). Meanwhile, acetone:DMF-diluted 11:1 PCL/green tea extract fiber produced smaller average (896 � 269 nm) and range of fiber diameter (1375 nm) compared to acetone:DMF-diluted 10:2 PCL/green tea extract fiber which produced higher average (901 � 215 nm) and smaller range of fiber diameter (1200 nm). In comparing between the two different solvent-system used, chloroform:DMF-diluted PCL/green tea extract fibers yielded smaller average fiber diameter (601 � 673 nm) and smaller range of fiber diameter (310 � 1719 nm) and have formation of spherical beads. Whereas, for acetone:DMFdiluted PCL/green tea extract fibers yielded larger average fiber diameter (896 � 1104 nm) and larger range of fiber diameter (430 � 3644 nm), no formation of bead. The wettability and permeability analysis were not statistically significant to prove improved hydrophilicity property of the fibrous membranes. zulaihi UTM 52 p. Thesis (Sarjana Sains (Kejuruteraan Bioperubatan)) - Universiti Teknologi Malaysia, 2019 2025-03-12T05:55:12Z 2025-03-12T05:55:12Z 2019 Master's thesis https://utmik.utm.my/handle/123456789/47642 vital:129978 valet-20191028-111858 ENG Closed Access UTM Complete Unpublished Completion application/pdf Universiti Teknologi Malaysia |
| spellingShingle | Biomedical engineering Health sciences Ainatul Aqilah Mohd. Rashid Fabrication and characterization of electrospunpoly(?-caprolactone) / green tea (camellia sinensis) extract fiber for wound healing |
| thesis_level | Master |
| title | Fabrication and characterization of electrospunpoly(?-caprolactone) / green tea (camellia sinensis) extract fiber for wound healing |
| title_full | Fabrication and characterization of electrospunpoly(?-caprolactone) / green tea (camellia sinensis) extract fiber for wound healing |
| title_fullStr | Fabrication and characterization of electrospunpoly(?-caprolactone) / green tea (camellia sinensis) extract fiber for wound healing |
| title_full_unstemmed | Fabrication and characterization of electrospunpoly(?-caprolactone) / green tea (camellia sinensis) extract fiber for wound healing |
| title_short | Fabrication and characterization of electrospunpoly(?-caprolactone) / green tea (camellia sinensis) extract fiber for wound healing |
| title_sort | fabrication and characterization of electrospunpoly caprolactone green tea camellia sinensis extract fiber for wound healing |
| topic | Biomedical engineering Health sciences |
| url | https://utmik.utm.my/handle/123456789/47642 |
| work_keys_str_mv | AT ainatulaqilahmohdrashid fabricationandcharacterizationofelectrospunpolycaprolactonegreenteacamelliasinensisextractfiberforwoundhealing |