Cloning and expression of heterologous human cytochrome P450 3A4-NADPH P450 reductase in Escherichia Coli / Ainul Zahiah Abdul Malik

Cytochrome P450 3A4 (CYP3A4) is one of the Cytochrome P450 monooxygenases, dominant in drug metabolism in human liver by virtue of its high levels of expression in liver and other tissues. It represents about 30% of total CYP450. The aim of this study is to develop a heterologous in vitro drug metab...

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Bibliographic Details
Main Author: Abdul Malik, Ainul Zahiah
Format: Thesis
Language:English
Published: 2010
Subjects:
Online Access:https://ir.uitm.edu.my/id/eprint/99244/1/99244.pdf
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