The Binding Of Bifidobacterium Pseudocatenulatum G4 Tomutagenic/Carcinogenic Heterocyclic Aromatic Aminesin An In Vitro Study

Consumption of probiotic microorganisms has been associated with decreased risk of colon cancer and reported to have antimutagenic/anticarcinogenic properties. Lactic acid bacteria (LAB) existing in the colon may exert an anticarcinogenic action, but the mechanism is still poorly understood. One...

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主要作者: Faridnia, Farnaz
格式: Thesis
語言:英语
英语
出版: 2010
主題:
在線閱讀:http://psasir.upm.edu.my/id/eprint/12012/1/FSTM_2010_1_A.pdf
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author Faridnia, Farnaz
author_facet Faridnia, Farnaz
author_sort Faridnia, Farnaz
description Consumption of probiotic microorganisms has been associated with decreased risk of colon cancer and reported to have antimutagenic/anticarcinogenic properties. Lactic acid bacteria (LAB) existing in the colon may exert an anticarcinogenic action, but the mechanism is still poorly understood. One possible mechanism for this effect involves physical binding of the mutagenic compounds, such as heterocyclic amines, to the bacteria. Therefore, the purpose of this study was to study the binding assay of mutagenic/carcinogenic heterocyclic aromatic amines (HCAs) to Bifidobacterium pseudocatenulatum G4, a species which has not been explored yet as a commercial probiotic, in vitro. The effect of two gram positive bacteria: Bifidobacterium pseudocatenulatum G4 and Bifidobacterium longum BB536 (a commercial probiotic used as a reference strain), and a gram negative bacterium: human intestinal strain Escherichia coli ATCC 25922 at the colon environmental pH and temperature were studied.
format Thesis
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language English
English
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spelling oai:psasir.upm.edu.my:120122013-05-27T07:50:47Z http://psasir.upm.edu.my/id/eprint/12012/ The Binding Of Bifidobacterium Pseudocatenulatum G4 Tomutagenic/Carcinogenic Heterocyclic Aromatic Aminesin An In Vitro Study Faridnia, Farnaz Consumption of probiotic microorganisms has been associated with decreased risk of colon cancer and reported to have antimutagenic/anticarcinogenic properties. Lactic acid bacteria (LAB) existing in the colon may exert an anticarcinogenic action, but the mechanism is still poorly understood. One possible mechanism for this effect involves physical binding of the mutagenic compounds, such as heterocyclic amines, to the bacteria. Therefore, the purpose of this study was to study the binding assay of mutagenic/carcinogenic heterocyclic aromatic amines (HCAs) to Bifidobacterium pseudocatenulatum G4, a species which has not been explored yet as a commercial probiotic, in vitro. The effect of two gram positive bacteria: Bifidobacterium pseudocatenulatum G4 and Bifidobacterium longum BB536 (a commercial probiotic used as a reference strain), and a gram negative bacterium: human intestinal strain Escherichia coli ATCC 25922 at the colon environmental pH and temperature were studied. 2010-01 Thesis NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/12012/1/FSTM_2010_1_A.pdf Faridnia, Farnaz (2010) The Binding Of Bifidobacterium Pseudocatenulatum G4 Tomutagenic/Carcinogenic Heterocyclic Aromatic Aminesin An In Vitro Study. Masters thesis, Universiti Putra Malaysia. Bifidobacterium Carcinogens Mutagens English
spellingShingle Bifidobacterium
Carcinogens
Mutagens
Faridnia, Farnaz
The Binding Of Bifidobacterium Pseudocatenulatum G4 Tomutagenic/Carcinogenic Heterocyclic Aromatic Aminesin An In Vitro Study
title The Binding Of Bifidobacterium Pseudocatenulatum G4 Tomutagenic/Carcinogenic Heterocyclic Aromatic Aminesin An In Vitro Study
title_full The Binding Of Bifidobacterium Pseudocatenulatum G4 Tomutagenic/Carcinogenic Heterocyclic Aromatic Aminesin An In Vitro Study
title_fullStr The Binding Of Bifidobacterium Pseudocatenulatum G4 Tomutagenic/Carcinogenic Heterocyclic Aromatic Aminesin An In Vitro Study
title_full_unstemmed The Binding Of Bifidobacterium Pseudocatenulatum G4 Tomutagenic/Carcinogenic Heterocyclic Aromatic Aminesin An In Vitro Study
title_short The Binding Of Bifidobacterium Pseudocatenulatum G4 Tomutagenic/Carcinogenic Heterocyclic Aromatic Aminesin An In Vitro Study
title_sort binding of bifidobacterium pseudocatenulatum g4 tomutagenic carcinogenic heterocyclic aromatic aminesin an in vitro study
topic Bifidobacterium
Carcinogens
Mutagens
url http://psasir.upm.edu.my/id/eprint/12012/1/FSTM_2010_1_A.pdf
url-record http://psasir.upm.edu.my/id/eprint/12012/
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