Design, synthesis, and biochemical assay of peptide inhibitors derived from α-enolase for use against peptidylarginine deiminase type 4
Rheumatoid arthritis (RA) is an inflammatory autoimmune disease affecting about 0.5–1.0% of the world population. Peptidylarginine deiminase type 4 (PAD4) is a responsible protein for the occurrence of RA by catalyzing citrullination of proteins. The citrullinated proteins act as autoantigens by sti...
| 第一著者: | |
|---|---|
| フォーマット: | 学位論文 |
| 言語: | 英語 |
| 出版事項: |
2013
|
| 主題: | |
| オンライン･アクセス: | http://psasir.upm.edu.my/id/eprint/67427/1/FS%202013%2059%20IR.pdf |