Dynamics of epigenetic control on transgene expression mediated by lentivirus in mouse pluripotent stem cells

Autologous transplantation of patient specific iPS-derived cells for ex vivo gene therapy application could be the only curative option for patients that do not have compatible donor. One of the limitations of successful gene therapy is short-lived duration of transgene expression in mammalian cells...

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Auteur principal: Alhaji, Suleiman Yusuf
Format: Thèse
Langue:anglais
Publié: 2018
Accès en ligne:http://psasir.upm.edu.my/id/eprint/76397/1/FPSK%28P%29%202018%2018%20-%20IR.pdf