Benzimidazole derivatives as potential dual inhibitors for poly (adp-ribose) polymerase-1 and dihydroorotate dehydrogenase / Iskandar Abdullah
Poly (ADP-ribose) polymerases (PARPs) play diverse roles in various cellular processes that involve DNA repair and programmed cell death. Amongst these polymerases is PARP-1, which is the key DNA damage-sensing enzyme that acts as an initiator for the DNA repair mechanism. Dihydroorotate dehydrogen...
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| フォーマット: | 学位論文 |
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2015
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