Alpha-lipoic acid and mesuagenin c-induced co-regulation of nf-κβ-cytokines and chemokines via pi3k-akt/gsk-3β and erk1/2 in in vitro neuronal models / Muhamad Noor Alfarizal Kamarudin

(R-)(+)-α-lipoic acid and mesuagenin c were shown to protect the NG108-15 cells against H2O2-induced cell death by mitigating the caspase-dependent mitochondrial-mediated pathway. (R)-(+)-α-lipoic acid activated both mTORC1 and mTORC2 components whereas mesuagenin c only activated mTORC2 component w...

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