p53-Mdm2 interaction targeted therapy by Nutlin-3 on nasopharyngeal carcinoma cells / Voon Yee Lin
Nutlin-3, a small-molecule inhibitor of p53-Mdm2 interaction, is known to be effective against cancers expressing wild-type (wt) p53. p53 mutations are rare in nasopharyngeal carcinoma (NPC), and hence targeting the disruption of p53-Mdm2 interaction to reactivate p53 may offer a promising therap...
| 主要作者: | Voon, Yee Lin |
|---|---|
| 格式: | Thesis |
| 出版: |
2016
|
| 主题: |
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相似书籍
-
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由: Lee, Sau Har
出版: (2013) -
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出版: (2015) -
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出版: (2016) -
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由: Choon, Yee Fan
出版: (2007)