Nanoparticulate Brain-Derived Neurotrophic Factor (BDNF) as a Potential Antidepressant via Neuroendocrine Mechanisms in Experimental Model of Depression

The hypothalamo-hypophyseal-adrenal axis (HHAA) links neurogenesis, neurotransmission, and immunoendocrine factors in depression. Stress-induced HHAA activation lowers brain-derived neurotrophic factor (BDNF) in the hippocampus, causing atrophic changes and depressive symptoms. Traditional antidepre...

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Bibliographic Details

Main Author:	Nur Amirah Diyana, Binti Razlan
Format:	Thesis
Language:	English English English
Published:	Universiti Malaysia Sarawak 2025
Subjects:	RZ Other systems of medicine
Online Access:	http://ir.unimas.my/id/eprint/48563/
Abstract	Abstract here