Influence of tert gene expression, telomerase activity and telomere length in relation to imatinib mesylate resistance in Malaysian chronic myeloid leukaemia patients

Chronic myeloid leukaemia (CML) is a myeloproliferative neoplasm diagnosed by the presence of the BCR-ABL fusion gene which produces a tyrosine kinase to signal a proliferation of white blood cells. The introduction of imatinib mesylate in early 2000, has dramatically increased the survival of af...

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Bibliographic Details
Main Author: Shamshudin, Wati @ Hayati Mohd
Format: Thesis
Language:English
Published: 2020
Subjects:
Online Access:http://eprints.usm.my/49320/