Behavioural, Biochemical, Proteomics Studies And Replacement Therapy Of Morphine And Mitragynine Withdrawal Rat Models
The current study was designed to test the ability of mitragynine to attenuate behavioural signs of morphine-withdrawal in a rat model in comparison to methadone and buprenorphine. A six-day treatment with escalating dose of morphine (10-50 mg/kg, i.p.) induced profound withdrawal signs for 16 days.
| 主要作者: | |
|---|---|
| 格式: | Thesis |
| 語言: | 英语 |
| 出版: |
2021
|
| 主題: | |
| 在線閱讀: | http://eprints.usm.my/53633/ |