Evaluation Of Toxicity, Pharmacokinetic And Clastogenicity Profile Of Ethyl 2-[4[(Piperidin-1-yl) Phenyl]-1h-benzimidazole-5-carboxylate (Bzd9l1), Novel Sirtuin Inhibitor

The mammalian sirtuins (SIRTs) have been linked to various diseases including cancer, diabetes, neurodegenerative and cardiovascular diseases. Thus, SIRTs are attractive targets for the development of pharmaceuticals. The lack of potential SIRT inhibitors in cancer clinical trials highlights the nee...

وصف كامل

التفاصيل البيبلوغرافية
المؤلف الرئيسي: Lee, Yeuan Ting
التنسيق: أطروحة
اللغة:الإنجليزية
منشور في: 2022
الموضوعات:
الوصول للمادة أونلاين:http://eprints.usm.my/59372/
Abstract Abstract here