Evaluation Of Toxicity, Pharmacokinetic And Clastogenicity Profile Of Ethyl 2-[4[(Piperidin-1-yl) Phenyl]-1h-benzimidazole-5-carboxylate (Bzd9l1), Novel Sirtuin Inhibitor
The mammalian sirtuins (SIRTs) have been linked to various diseases including cancer, diabetes, neurodegenerative and cardiovascular diseases. Thus, SIRTs are attractive targets for the development of pharmaceuticals. The lack of potential SIRT inhibitors in cancer clinical trials highlights the nee...
| المؤلف الرئيسي: | Lee, Yeuan Ting |
|---|---|
| التنسيق: | أطروحة |
| اللغة: | الإنجليزية |
| منشور في: |
2022
|
| الموضوعات: | |
| الوصول للمادة أونلاين: | http://eprints.usm.my/59372/ |
| Abstract | Abstract here |
مواد مشابهة
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مواد مشابهة
-
Mechanism Of Action Of A Benzimidazole Sirtuin Inhibitor, Bzd9l1, In Colorectal Cancer
حسب: Tan, Yi Jer
منشور في: (2022) -
Synthesis And Biological Activity Of Benzimidazole Analogs As Sirtuin Enzyme Inhibitors
حسب: Yeong, Keng Yoon
منشور في: (2016) -
Bzd9l1: Elucidation Of Its Anti-angiogenic Potential In In-vitro And In-vivo Colorectal Cancer Models
حسب: Subramaniam, Ayappa V.
منشور في: (2023) -
Pharmacokinetics And Metabolism Studies
Of Antifilarial Drugs
Derivatives Of Benzimidazole Carbamate
حسب: Ramanathan, Surash
منشور في: (1996) -
Benzimidazole derivatives as potential dual inhibitors for poly (adp-ribose) polymerase-1 and dihydroorotate
dehydrogenase / Iskandar Abdullah
حسب: Iskandar, Abdullah
منشور في: (2015)
