Synthesis, Characterization Of 1,3-Diarylpropenes And Tricyclic Indolines And The Cytotoxic Activities Of 1,3-Diarylpropenes

Alkaloids are crucial nitrogen-containing compounds that exhibit diverse biological and pharmaceutical activity, regardless of the compound scaffold. Accordingly, it drives the synthesis of amido 1,3-diarylpropene and 6-5-4 tricyclic indoline under the alkaloid class, potentially the chemotherapeut...

詳細記述

書誌詳細
第一著者: Tan, Aik Sian
フォーマット: 学位論文
言語:英語
出版事項: 2022
主題:
オンライン・アクセス:http://eprints.usm.my/59746/
その他の書誌記述
要約:Alkaloids are crucial nitrogen-containing compounds that exhibit diverse biological and pharmaceutical activity, regardless of the compound scaffold. Accordingly, it drives the synthesis of amido 1,3-diarylpropene and 6-5-4 tricyclic indoline under the alkaloid class, potentially the chemotherapeutic agents for cancer treatment. In the first study, forty (40) 1,3-diarylpropene derivatives, designed analogs of stilbenoids and dihydrostilbenoids, were synthesized by the palladiumcatalyzed reactions of 2-amidoiodobenzene derivatives with either estragole or eugenol.