Ultra-high performance liquid chromatography (uhplc) method development and validation for the determination of serum imatinib and its active metabolite concentration among chronic myeloid leukemia patients

A simple and sensitive method for the simultaneous detection of imatinib mesylate and its active metabolite, N-desmethylimatinib, in human serum samples was developed. Separation was successfully achieved using an Agilent® ZORBAX Eclipse plus Cis reversed phase column (50 x 2.1 mm, i.d.; 1.8 pm) u...

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Bibliographic Details

Main Author:	Liong, Tan Ka
Format:	Thesis
Language:	English
Published:	2013
Subjects:	R Medicine RC254-282 Neoplasms. Tumors. Oncology (including Cancer) RC648-665 Diseases of the endocrine glands. Clinical endocrinology
Online Access:	http://eprints.usm.my/60900/