An in vitro study of stereoselectivity of cytochrome p450 enzymes in the metabolism of 3,4-methylenedioxymethamphetamine

Cytochrome P450 (CYP) enzymes metabolise 3,4- methylenedioxymethamphetamine (MDMA). MDMA is a neurotoxic drug of abuse with stimulant and hallucinogenic properties. Its metabolism is stereoselective with (S)-MDMA preferred over (fl)-MDMA. Since MDMA stereoisomers possess different pharmacokineti...

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Détails bibliographiques
Auteur principal:	Asim, Wan Raihana Wan Aasim @ Wan
Format:	Thèse
Langue:	anglais
Publié:	2013
Sujets:	R Medicine RA440-440.87 Study and teaching. Research
Accès en ligne:	http://eprints.usm.my/60902/

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