An in vitro study of stereoselectivity of cytochrome p450 enzymes in the metabolism of 3,4-methylenedioxymethamphetamine
Cytochrome P450 (CYP) enzymes metabolise 3,4- methylenedioxymethamphetamine (MDMA). MDMA is a neurotoxic drug of abuse with stimulant and hallucinogenic properties. Its metabolism is stereoselective with (S)-MDMA preferred over (fl)-MDMA. Since MDMA stereoisomers possess different pharmacokineti...
| 第一著者: | |
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| フォーマット: | 学位論文 |
| 言語: | 英語 |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | http://eprints.usm.my/60902/ |