The Evaluation Of Endoplasmic Reticulum Stress Among Regular Kratom Users And Its Implications For Kratom Dependence And Kratom Induced Depressive Symptoms
Recent research showed that psychoactive substances can induce endoplasmic reticulum (ER) stress and unfolded protein response (UPR). This case-control study filled the research gap by: (1) determining the association between kratom use characteristics (such as the age of first kratom use, the durat...
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| Format: | Thesis |
| Language: | English |
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2024
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| Online Access: | http://eprints.usm.my/63138/ |
| Abstract | Abstract here |
| _version_ | 1854969851264630784 |
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| author | Yang, Bin |
| author_facet | Yang, Bin |
| author_sort | Yang, Bin |
| description | Recent research showed that psychoactive substances can induce endoplasmic reticulum (ER) stress and unfolded protein response (UPR). This case-control study filled the research gap by: (1) determining the association between kratom use characteristics (such as the age of first kratom use, the duration of kratom use, the average frequency and quantity of daily kratom use, and the time since last kratom consumption prior to blood collection for analysis) and the mRNA and protein expression of ER stress sensors; and (2) assessing the correlations between the mRNA and protein expression of ER stress sensors and severity of kratom dependence and kratom induced depressive symptoms during kratom abstinence. |
| first_indexed | 2025-12-24T00:13:38Z |
| format | Thesis |
| id | usm-63138 |
| institution | Universiti Sains Malaysia |
| language | English |
| last_indexed | 2025-12-24T00:13:38Z |
| publishDate | 2024 |
| record_format | eprints |
| record_pdf | Abstract |
| spelling | usm-631382025-10-30T00:49:48Z http://eprints.usm.my/63138/ The Evaluation Of Endoplasmic Reticulum Stress Among Regular Kratom Users And Its Implications For Kratom Dependence And Kratom Induced Depressive Symptoms Yang, Bin R5-920 Medicine (General) Recent research showed that psychoactive substances can induce endoplasmic reticulum (ER) stress and unfolded protein response (UPR). This case-control study filled the research gap by: (1) determining the association between kratom use characteristics (such as the age of first kratom use, the duration of kratom use, the average frequency and quantity of daily kratom use, and the time since last kratom consumption prior to blood collection for analysis) and the mRNA and protein expression of ER stress sensors; and (2) assessing the correlations between the mRNA and protein expression of ER stress sensors and severity of kratom dependence and kratom induced depressive symptoms during kratom abstinence. 2024-03 Thesis NonPeerReviewed application/pdf en http://eprints.usm.my/63138/1/Pages%20from%20YANG%20BIN%20-%20TESIS.pdf Yang, Bin (2024) The Evaluation Of Endoplasmic Reticulum Stress Among Regular Kratom Users And Its Implications For Kratom Dependence And Kratom Induced Depressive Symptoms. PhD thesis, Universiti Sains Malaysia. |
| spellingShingle | R5-920 Medicine (General) Yang, Bin The Evaluation Of Endoplasmic Reticulum Stress Among Regular Kratom Users And Its Implications For Kratom Dependence And Kratom Induced Depressive Symptoms |
| title | The Evaluation Of Endoplasmic Reticulum Stress Among Regular Kratom Users And Its Implications For Kratom Dependence And Kratom Induced Depressive Symptoms |
| title_full | The Evaluation Of Endoplasmic Reticulum Stress Among Regular Kratom Users And Its Implications For Kratom Dependence And Kratom Induced Depressive Symptoms |
| title_fullStr | The Evaluation Of Endoplasmic Reticulum Stress Among Regular Kratom Users And Its Implications For Kratom Dependence And Kratom Induced Depressive Symptoms |
| title_full_unstemmed | The Evaluation Of Endoplasmic Reticulum Stress Among Regular Kratom Users And Its Implications For Kratom Dependence And Kratom Induced Depressive Symptoms |
| title_short | The Evaluation Of Endoplasmic Reticulum Stress Among Regular Kratom Users And Its Implications For Kratom Dependence And Kratom Induced Depressive Symptoms |
| title_sort | evaluation of endoplasmic reticulum stress among regular kratom users and its implications for kratom dependence and kratom induced depressive symptoms |
| topic | R5-920 Medicine (General) |
| url | http://eprints.usm.my/63138/ |
| work_keys_str_mv | AT yangbin theevaluationofendoplasmicreticulumstressamongregularkratomusersanditsimplicationsforkratomdependenceandkratominduceddepressivesymptoms AT yangbin evaluationofendoplasmicreticulumstressamongregularkratomusersanditsimplicationsforkratomdependenceandkratominduceddepressivesymptoms |