The characterisation of mdm2 and cdk4 gene amplification and their association with recurrence in lipomatous tumours

MDM2 and CDK4 are frequently amplified genes in liposarcoma, particularly in atypical lipomatous tumour/well-differentiated liposarcoma (ALT/WDLS) and dedifferentiated liposarcoma (DDLS). Although the individual oncogenic role of MDM2 and CDK4 genes are well established, the prevalence and ratio of...

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Bibliographic Details
Main Author: James, Jessinntha Spt
Format: Thesis
Language:English
Published: 2025
Subjects:
Online Access:http://eprints.usm.my/63183/
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