Chiral separation of ketoconazole and itraconazole anti-fungal drugs using experimental and computational approaches

Drugs with multiple chiral centers were observed as very effective for treating various diseases. However, the enantiomeric resolution of multiple chiral center racemates is not much developed compared to racemates having a single asymmetric center. This work aimed to develop a chiral separation met...

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Détails bibliographiques
Auteur principal: Arsad, Siti Rosilah
Format: Thèse
Langue:anglais
Publié: 2019
Sujets:
Accès en ligne:http://eprints.utm.my/101945/1/SitiRosilahPhDFS2019.pdf